Asacol is the brand name for the generic drug mesalamine. This prescription medication is indicated to treat patients with ulcerative colitis, an inflammatory bowel disease. Asacol is a type of antiinflammatory drug that limits production of inflammatory and pain signals in the body. Despite the benefits of this medication, certain patients should not use Asacol. A doctor should discuss Asacol contraindications with patients before prescribing this medication.
Under Age 18
The efficacy and safety of Asacol have not been clincally evaluated in pediatric patients, RxList reports. Children under the age of 18 should not use this medication unless otherwise indicated by a medical professional.
Pregnant or Breastfeeding
The U.S. Food and Drug Administration has assigned this medication to Pregnancy Category C. Women who are pregnant or breastfeeding should avoid using Asacol due to the potential risk of fetal or infant injury or developmental problems.
Kidney Dysfunction or Disease
Treatment with Asacol can cause renal or kidney inflammation, impairment and even kidney failure in certain patients, RxList explains. Patients with preexisting kidney dysfunction or disease should avoid using this medication in order to prevent further kidney complications.
Allergic to Mesalamine, Aspirin or Salicylates
Patients who are allergic to mesalamine, aspirin or other types of salicylate medications should not receive treatment with Asacol, Drugs.com advises. Hypersensitive patients treated with Asacol can experience anaphylaxis, a severe, potentially life-threatening allergic reaction.
