Zyvox, known generically as linezolid, is an antibiotic drug used to treat complicated bacterial infections. Zyvox is most commonly prescribed to combat pneumonia, urinary tract infections and infections of the skin or blood. The side effects of Zyvox are generally mild and not dangerous. Some side effects of Zyvox are more severe and more likely to occur if Zyvox is used for a prolonged period of time. Patients using Zyvox for more than two weeks should be monitored by a physician for such side effects.
Seizures
Convulsions and seizures have been reported as side effects of Zyvox use. Drug consumer safety information provided by Pfizer, the maker of Zyvox, explains that patients with a history of seizures and convulsions may be at an increased risk for developing further seizures while using Zyvox.
Increased Bleeding Risk
According to Drugs.com, Zyvox can be harmful to certain important types of blood cells, particularly blood platelets. Platelets are a type of blood cell necessary for the process of blood clotting. When platelet levels become too low, a condition known as thrombocytopenia, a person can have problems clotting blood upon injury. Individuals with low platelet counts are also more likely to suffer from internal bleeding, especially if they already have certain conditions such as ulcers. This effect is most likely to occur in people taking Zyvox for an extended period of time. Other blood cells important for immune function can also be damaged by Zyvox use. It is recommended that patients using Zyvox be monitored weekly for levels of certain blood cells, particularly if treatment lasts longer than two weeks.
Optic Neuropathy
Zyvox use can cause problems with vision. Individuals using Zyvox for more than two weeks are at risk of developing optic neuropathy, a degeneration of the nerves that send impulses from the eyes to the brain. HealthSquare.com explains symptoms of optic neuropathy in response to Zyvox can include blurred vision and loss of color vision. In rare cases, overuse of Zyvox may lead to total and permanent blindness.
Secondary Infections
While Zyvox kills harmful bacteria at the root of a dangerous infection, it can also kill bacteria needed for healthy functioning. As Zyvox kills friendly bacteria, it opens up a space for other infections to occur, particularly fungal infections. Drugs.com explains that a number of fungal infections, including vaginal yeast infections and infections in the mouth, are common with Zyvox use. A number of other bacterial infections are also associated with Zyvox use. Drugs.com explains that Clostridium difficile, or C. diff, infections are common with Zyvox use. While these C. diff infections typically result in mild symptoms such as diarrhea, they are potentially fatal, especially in immunosuppressed patients who may be using Zyvox to combat other infections.
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