What Are The Effects Of Namenda?

Namenda, or memantine, is used to treat the symptoms associated with moderate to severe Alzheimer's type dementia. It works by reducing the brain's abnormal activity. It is not a cure, nor does it slow the progression of the disease.

Blocks the Effects of Glutamate

Memantine is believed to block the effect of glutamate, the main excitatory chemical in nerve cells, thus reducing the degeneration of nerve cells in Alzheimer's patients. Over-stimulation of some nerve cells by glutamate leads to the death of these cells and consequent atrophy, or shrinking, of the brain over time, according to American Hospice Foundation.

Adverse Effects

Namenda may cause dizziness, headache and coughing. Fainting, high blood pressure, heart failure and stroke were frequently reported in clinical trials, according to Drugs. com, as were dizziness and balance problems. Common symptoms of heart failure include shortness of breath and ankle swelling. Anemia, aggression, cataract and conjunctivitis were also reported frequently in test trials, and constipation occurred, as well.

Less Frequent Side Effects

Chest pain, heart attack, low blood pressure and seizures are less common heart-related and neurological side effects of Namenda. Reduced white blood cell count may occur, as well. Itching, rashes and baldness are additional less frequent side effects, and decreased hearing and blurred vision have also been reported.