Psoriasis is a condition in which the immune system attacks skin cells, resulting in rapid skin cell proliferation. The rapidly dividing cells can cause large raised plaques to form on many areas of the body, including the hands.
Corticosteroids and Hands
Chronic psoriasis of the hands can be treated using corticosteroid creams, which can be applied directly to the affected skin regions, MayoClinic.com explains. Because the skin on the hands is relatively thick, more potent corticosteroid creams may be needed to fully penetrate the multiple skin layers.
Mechanism
Corticosteroids are a class of drugs that inhibit inflammation, the National Psoriasis Foundation reports. Because inflammation is the trigger of the cell proliferation, which causes psoriasis skin lesions, the use of topical corticosteroids can help reduce the redness and itching of active outbreaks of psoriasis.
Side Effects
Even when used topically, corticosteroids can have a number of side effects, the National Institute of Arthritis and Musculoskeletal and Skin Diseases explains. Long-term use of corticosteroids can result in thinning of the skin, suppression of the immune system, high blood sugar and resistance of psoriasis to corticosteroid treatment.


