Fexofenadine HCl, sold under the brand name Allegra, is an antihistamine used to treat the symptoms of seasonal allergies. It may also be used for chronic idiopathic urticaria, which is chronic hives of unknown reason. The medication competes with histamine, which is a chemical that leads to inflammation and inflammatory reactions in the body. This leads to a reduction in allergy symptoms and hives. Like any drug, fexofenadine may produce several side effects.
Headache
Headaches are commonly seen in patients on fexofenadine 180 mg. About five to 11 percent of individuals may develop headaches, according to the "Drug Information Handbook." A pain killer, such as ibuprofen, may help alleviate a headache. Before using an over-the-counter medication, however, the patient should speak with a health care professional to avoid drug interactions and complications. Headache is a side effect that diminishes with time. If a headache worsens, the patient should contact a physician right away.
Nausea and Diarrhea
Nausea and upset stomach may occur in patients using fexofenadine 180 mg. Mayoclinic.com reports that vomiting is a common gastrointestinal side effect, as well. This medication should be taken on an empty stomach, but drinking plenty of water may help with these side effects. Diarrhea is another side effect of fexofenadine that may occur in up to four percent of individuals. The patient should avoid large meals with a high fat content. Over-the-counter medications may alleviate this adverse reaction; however, the patient should ask a health care professional which medication is safe to use. If diarrhea persists or worsens, the patient should seek medical attention.
Back Pain
According to Allegra.com, patients who are on fexofenadine 180 mg for the treatment of seasonal allergies may experience back pain. Up to three percent of individuals may develop this side effect. Back pain is not harmful and may be treated with acetaminophen, as long as a patient speaks with a physician or pharmacist first. If backache worsens or is accompanied by other symptoms, such as muscle aches and fever, it may be a sign of something more serious and requires medical attention.
Upper Respiratory Tract Infection
Patients who are on fexofenadine 180 mg may develop an upper respiratory tract infection. According to Merck.com, about three to four percent of patients may experience this adverse effect. The symptoms of an upper respiratory tract infection include runny nose, sore throat, cough and fever. The patient should contact a physician if these symptoms occur. A physician can determine if the patient needs to be treated with other medications.
References
- "Drug Information Handbook"; Charles F. Lacy, Lora L. Armstrong, et al.; 2009
- MayoClinic.com: Fexofenadine
- Allegra.com: Important Safety Information
- Merck.com: Fexofenadine



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