Tylenol PM is a medication that combines acetaminophen and diphenhydramine, which is an antihistamine, according to Drugs.com. The medication is primarily meant to relieve symptoms associated with allergic reactions, but it is also used to treat nighttime pain and help you sleep. When taken as recommended, Tylenol PM is highly effective against the pain and fever brought on by allergies and influenza, notes Drugs.com. However, even normal dosages can cause a variety of adverse side effects.
Anxiety and Restlessness
Tylenol PM can cause anxiety and restlessness, notes Drugs.com. Anyone experiencing such effects should cease taking the medication and seek medical advice. Such excitement or restlessness can typically strike children, notes MedlinePlus.
Appetite Loss
Tylenol PM can cause a loss of appetite, notes MedlinePlus. Current data suggest that appetite loss may occur in relation to alcohol abuse or possible overdose, explains Drugs.com.
Arrhythmia and Decreased Blood Pressure
Tylenol PM can cause arrhythmia, notes the University of Maryland Medical Center. Data also show that Tylenol PM causes blood pressure to drop, but the medication can also cause an increase in heart rate, explains Drugs.com.
Dryness
Tylenol PM can cause dryness of the eyes and nose, note MedlinePlus and Drugs.com. The medication may also cause the mouth and throat to dry as well.
Dizziness and Impaired Cognition
Tylenol PM may cause dizziness. The dizziness may be extreme and accompanied by a sense of confusion, notes Drugs.com. Tylenol PM may also impair cognition, notes the University of Maryland Medical Center.
Jaundice and Low-Grade Fever
Tylenol PM can cause jaundice, notes Drugs.com. The medication may also cause low-grade fever.
Less Frequent Urination
Tylenol PM can reduce urination frequency, notes Drugs.com. The act of urinating may also be painful, and the pain can make urinating difficult.
Liver Damage
Tylenol PM has caused liver damage in patients with a history of alcohol abuse, notes Drugs.com. Data suggest that the damage to the liver may be causing the liver to deplete its glutathione supply. Glutathione is an important biochemical involved in cellular respiration.
Nausea and Pain
Evidence shows that taking Tylenol PM may cause nausea and pain in the abdominal region, notes MedlinePlus. The medication may also sometimes damage the pancreas, notes Drugs.com.
Daytime Sleepiness and Vision Problems
Tylenol PM can cause sleepiness during daylight hours, notes the University of Maryland Medical Center. The medicine may also cause vision problems.
Swelling
Taking Tylenol PM can cause an allergic reaction, such as swelling around the facial and throat region, explains Drugs.com. In addition, the oral region can also swell if the patient is allergic to Tylenol PM. Seeking the advice of a medical expert is highly recommended if this occurs.
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