Yohimbe is a naturally occurring herb that causes a variety of reactions when ingested. It is included in numerous supplements and sold as an aid for weight loss, sexual enhancement and libido, and depression. Unfortunately, yohimbe can also be a cause of many adverse health risks.
Learn about the positive and negative impacts of yohimbe and consult a doctor before beginning consumption. Note that this supplement is not intended to treat or prevent any diseases or pre-existing health conditions.
Active Ingredients
Yohimbe is derived from the bark of a western Africa evergreen tree. Although it contains numerous alkaloids, the active ingredient is known as yohimbine, and this is the primary chemical responsible for the effects of yohimbe bark as a whole--positive and negative. Many supplements include the ingredient yohimbe, but the varying strengths of the bark equate to different amounts of the active yohimbine, as such, it is difficult to gauge the potency of each. A safer and cheaper alternative would be to purchase the extract itself, and dose accordingly.
From this point on, the herb will be referred to as yohimbine, as this is the active, and only, ingredient in yohimbe bark.
Yohimbine and Fat Loss
One of the primary hormones responsible for lipolysis, or fat burning, in the body is norepinephrine. The release of this hormone results in the stimulation of two receptors, one to initiate the breakdown of fat cells to be burned as energy, and the other as a feedback mechanism to limit the effects of the first. After enough time passes, norepinephrine levels are regulated, and the process stops. Yohimbine is an efficient fat burner due to its ability to not only release norepinehprine and simulate lipolysis, but also because it blocks the alpha(2) adenoreceptors that regulate its cessation. This amounts to an increase in the body's fat burning capabilities at periods of rest as well as exercise. In addition, the alpha (2) adenoreceptors are found in higher concentrations in the "trouble" areas for weight loss--notably the abdominal region in men, and thighs and glutes in women. By blocking these receptors, yohimbine also limits the storage of additional fat in these areas.
Note that in order for these effects to take place, yohimbine must be used in conjunction with a reduced calorie diet and plenty of exercise to facilitate fat loss.
Yohimbine and Depression
Evidence suggests that yohimbine plays a significant role in neurotransmitter receptor function, and has the ability to reverse some effects of depression. By blocking the enzyme monoamine oxidase, it can assist in the regulation of cortisol and norepinephrine in brain chemistry. The dosage necessary for such a response is often extremely high, and as such is not recommended without consultation with a doctor.
Yohimbine and Sexual Performance
In addition to enhancing libido and sexual desire, yohimbine has been proved to increase blood flow, especially to the extremities. Coupled with the increased nitric oxide circulation, it has been proposed as an effective remedy to erectile dysfunction and a performance aid.
Side Effects
Consistent use of yohimbine may result in an increase in blood pressure, anxiety, dizziness, and rapid heartbeat. Due to the narrow range of effectiveness in dosage, it is highly recommended to consult a doctor before usage, and avoid taking it if you are prone to any of these symptoms.
References
- Arch Gen Psychiatry, Alpha 2-adrenergic receptor function in depression. The cortisol response to yohimbine. Price LH, Charney DS, Rubin AL, Heninger GR., 1986
- Journal of Urology- Volume 159, Issue 2, YOHIMBINE FOR ERECTILE DYSFUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS, E. Ernst, M.H. Pittler, 1998



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