Adrenal disturbance exists in differing forms and ranges in severity. MayoClinic.com emphasizes that the terms "adrenal exhaustion" and "adrenal fatigue," are not medically recognized diagnoses, however, fatigue or exhaustion are symptoms apart of the clinically recognized condition known as Addison's disease. The adrenal glands make up an important portion of hormone secretion and play a significant role in the biological components of the stress response. Women to Women notes that a significant percentage of females experience impaired adrenal functioning, ranging from symptoms of mild stress to extreme exhaustion. Due to the possibility of developing an adrenal disorder, recognizing symptoms of adrenal dysfunction can aid in seeking the appropriate form of medical treatment.
Weakness and Fatigue
The body manages stress through secreting a hormone called corticotropin, which stimulates the adrenal glands in a process that produces corticosteroids, according to Merck Manuals Online Medical Library. Stress induces excessive release of these hormones, overworking the adrenal glands. Symptoms resulting from chronic stress or high levels of acute stress lead to fatigue, tiredness despite sufficient sleep and overall weakness. MayoClinic.com notes that these symptoms can start slowly and, depending on the exact adrenal condition, may worsen and limit daily activity significantly.
Depression and Irritability
Disturbance in mood, such as increased depression and irritability, accompany adrenal disturbance. The National Endocrine and Metabolic Diseases Information Service explains that these symptoms are common in the case of developing Addison's disease but can be present in less severe forms of adrenal conditions. Women to Women further notes that females experiencing these symptoms may also have higher cravings for carbohydrates, sugars and stimulants, such as caffeine, when adrenal imbalance is present. Often the symptoms are cyclical and perpetuate when the hormone imbalance is not treated.
Appetite, Sleep and Weight
The National Endocrine and Metabolic Diseases Information Service indicates that the adrenal glands affect the secretion of the hormone cortisol, which is vital in metabolic functioning and metabolism regulation. Increased stress alters cortisol levels and subsequently reduces appetite and consistent lack of appetite leads to weight loss. Sleep is impacted by this process as well and is altered either by insomnia or excessive sleepiness.
Pain and Blood Pressure
Lower back pain, leg pain and muscle aches are present in this condition, notes MayoClinic.com. The hormone aldosterone, which is produced by the adrenal glands is important in regulating blood pressure and potassium levels. The National Endocrine and Metabolic Diseases Information Service indicates that low levels of this hormone prevent the kidneys from regulating water and salt balance, which causes a drop in blood pressure.


