Proton pump inhibitors are a class of medications which inhibit the action of the parietal cells, which are found in parts of the lining of the stomach. The parietal cells are responsible for making stomach acid, which aids in the breakdown of food and also activates digestive enzymes. Some diseases, such as acid reflux and peptic ulcers, can be caused or exacerbated by stomach acid. For these conditions, proton pump inhibitors may be used to reduce the amount of acid in the stomach, thus providing relief for the underlying condition.
Step 1
Try nonprescription-strength proton pump inhibitors. Omeprazole, which is sold under the brand name Prilosec, is available in over-the-counter formulations as well as lansoprazole, which is sold under the brand name Prevacid, Consumer Reports explains. Although these over-the-counter formulations are less potent than their prescription counterparts, they contain the same active ingredients. These over-the-counter formulations represent a good starting point for patients looking to begin using proton pump inhibitors because they are significantly cheaper than prescription-strength products and can be obtained without going to a doctor. Try these varieties for a few weeks to see if they sufficiently relieve your symptoms. If the medications have some effect but do not completely control your heartburn or gastric ulcers, you can try and get a prescription for a stronger form.
Step 2
Choose a drug that has been approved for your gastric condition. Lansoprazole and omeprazole, the Veterans Health Administration explains, are the two proton pump inhibitors that have been approved by the U.S. Food and Drug Administration for the most digestive conditions, including the treatment of gastroesophageal reflux disease, gastric and duodenal ulcers and conditions which result in the hypersecretion of gastric acid. However, in some specific cases other proton pump inhibitors, such as pantoprazole and rabeprazole may be more effective.
Step 3
Compare costs. Both Consumer Reports and the Veterans Health Administration have concluded that there is not much difference in the clinical effectiveness of different varieties of proton pump inhibitors. As a result, cost may be a major factor in choosing a proton pump inhibitor. If you have an insurance policy which provides prescription medication coverage, check with your insurance provider to see if there is a difference for you in out-of-pocket costs among the different brands. Your pharmacy or doctor may also be able to advise you as to the cost of the different types of proton pump inhibitors, as well as whether there are generic forms available.
