Health care providers prescribe testosterone replacement therapy for both men and women whose serum testosterone levels are determined, through laboratory analysis, to be lower than the specified range. Although the ranges are different, the effects of a low testosterone level in men and women are comparable--low energy, decreased libido, weak bones and depression. Replacement therapy is available in several forms, including cream and transdermal patches. Each application delivers a premeasured dose of testosterone. If you and your doctor agree that replacement therapy is right for you, it is important that you understand the potential side effects.
Expected Side Effects
According to Drugs.com, expected side effects of testosterone replacement include sex drive variations, mouth and gum irritations including gum swelling and tenderness, headache and hair loss. You may also experience breast tenderness and/or enlargement, sudden changes in mood, headache and a disrupted sleep cycle.
Serious Side Effects
Serious side effects of testosterone replacement therapy are those that occur infrequently; however, they can be more severe. As stated by Drugs.com, you should seek medical attention should you experience symptoms of an allergic reaction, including hives and difficulty breathing. Since testosterone can affect liver function, talk to your doctor if you notice that your skin or the whites of your eyes appears yellow. The same is true should you develop breast tenderness and enlargement. Sudden changes in mood or behavior, including depression, warrant timely medical intervention, as well.
Secondary Exposure
Not as likely with the transdermal patch, the use of topical cream and gel has been associated with secondary exposure that can occur when another person comes in contact with the area of skin to which you applied the product. This can be particularly dangerous for children. For this reason, the U.S. Food and Drug Administration requires manufacturers of these medications to place clear warnings on and in their packaging.
The FDA reports that transfer of testosterone cream or gel to a child can result in symptoms comparable to those experienced during puberty, such as changes in behavior, as well as developmental changes including growth of pubic hair and development of genitalia. To avoid potential transfer, ensure that you are applying the cream on an area either covered by clothing, or one that is unlikely to come in contact with others.
