Colestipol, also known as Colestid and Colestid Flavored, according to Drugs.com, is marketed as a cholesterol drug designed to lower levels of bad cholesterol in the blood. MediResource notes that it works by binding with cholesterol being consumed, preventing it from accumulating in the blood. It is available in tablet form or as granules that are mixed with liquids. Like all medications that alter food digestion processes, Colestipol has side effects.
Damaged Teeth
According to Drugs.com, Colestipol is harmful to teeth. Medication that is not swallowed promptly without being chewed or that lingers in the mouth from a liquid suspension mixture can damage natural teeth. Drugs.com recommends following liquid dosages with a second glass of water to both ensure a full dose is received and mitigate this side effect.
Constipation
Constipation is a relatively common side effect of Colestipol, notes MediResource and Drugs.com. Severe constipation may be a sign of overdose, especially if accompanied by severe stomach pain.
Nausea or Vomiting
According to MediResource, nausea and vomiting are side effects of Colestipol that are experienced by about 1 percent of those who use the drug. Drugs.com also notes that Colestipol should never be taken on an empty stomach or within one hour of taking other medications partially due to the potential for upset stomach.
Hemorrhoids
As a result of taking Colestipol, patients may experience the side effect of hemorrhoids or aggravation of existing hemorrhoids, according to MediResource and the Natural News website. This side effect of Colestipol can be mitigated with increased fiber and fluid intakes throughout the course of treatment.
Blockage of Fat Soluble Nutrients
Colestipol works by binding with cholesterols in foods, notes MediResource, but it also intentionally reduces overall fat and nutrient absorption levels. This can have a dramatic effect on the levels of fat soluble nutrients being obtained from regular meals, according to the Natural News website.
Vitamin K Deficiency
MediResource notes that long-term use of Colestipol has been linked to vitamin K deficiency. Although this is a rare symptom, it can increase an individual's tendency to bleed when injured.
Phenylketonuria Complications
Individuals with phenylketonuria should beware of potential side effects from the granule form of Colestipol, notes MediResource. The granule blends contain phenylalanine at a rate of 18.2 mg per 7.5 g of granules.
