Nitric oxide supplements are popular options for strength athletes in need of a pre-workout intensity and energy boost. As the online training and supplement resource Bodybuilding.com explains, nitric oxide supplements may help increase blood flow, which may help deliver nutrients to muscle more efficiently as well as increase adrenaline release. Common ingredients in nitric oxide supplements include arginine and other amino acids, caffeine and other stimulants, and tribulus, which Bodybuilding.com claims may improve testosterone levels. Despite these purported effects, you may still experience side effects when using nitric oxide supplements, and you should consult a doctor before use.
Gastrointestinal Distress
According to research reported in the June 2007 issue of the Journal of Nutrition, several popular ingredients in nitric oxide supplements may cause gastrointestinal issues. The research indicates that amino acids such as arginine and citrulline have a history of digestive problems as side effects. The journal reports that nausea, diarrhea and irregular bowel movements may result from the use of these amino acids. In addition, some study participants reported minor to severe stomach cramps. The journal article suggests that lowering the dose of formulations containing these ingredients may be beneficial.
Low Blood Pressure
As the Mayo Clinic explains, arginine may improve blood flow through the process of vasodilation, which is a relaxation, or widening, of your blood vessels. However, alterations in your blood vessels can lead to side effects, and the Mayo Clinic notes that low blood pressure may result from the use of arginine. Because of this, you should consult a doctor before using arginine with any other medications that may cause changes in blood pressure.
Increase in Blood Sugar Levels
Another common ingredient in nitric oxide products, caffeine, may disturb your blood sugar levels. According to the Mayo Clinic, the rise in blood sugar levels is of most concern to those with type 2 diabetes. The Mayo Clinic explains that daily doses of 250 mg of caffeine may cause a significant increase in blood sugar levels. The clinic notes that caffeine interferes with the action of the hormone insulin. Insulin is used to convert food into energy, so you may experience swings in energy levels when using nitric oxide products.
Dizziness
According to the medical information website Drugs.com, another common side effect of caffeine is dizziness. This may be a result of the changes in blood pressure and blood sugar levels that caffeine creates. Dizziness may be more likely to occur when using nitric oxide products rather than caffeine alone because arginine also influences blood pressure.



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