Lupron, also known by the generic name leuprolide, is a type of medicine called a gonadotropin-releasing hormone used in pediatrics to treat central precocious puberty. According to Mayoclinic.com, central precocious puberty is a condition that causes early puberty in boys nine years old or younger and girls eight years old or younger. Lupron works by decreasing testosterone levels in boys and estrogen levels in girls, thus delaying puberty in children developing too early. Lupron is an injection that may be given daily, once a month or once every three months. While considered safe for pediatric use, Lupron does have some side effects that should be monitored for during treatment.
Injection Site Reactions
One of the most common side effect of Lupron is a skin reaction at the injection site. Children may experience pain, redness or tenderness after receiving an injection of Lupron. If your child requires daily injections, your pediatrician will teach you how to give Lupron at home. It is important to follow your doctor's directions precisely. Rotating the location of daily injections will allow already used areas to heal between uses. Your doctor will teach you which areas of the body are appropriate injection sites.
Mood Changes
Occasionally, children taking Lupron will experience changes in mood such as depression, anxiety or nervousness. Younger children may feel that something is wrong but be unable to effectively verbalize what they are feeling. These children may present as withdrawn, irritable or unable to focus on a task. If these symptoms persist or are severe, contact your pediatrician right away. Your doctor will evaluate your child and decide if continuing Lupron therapy is appropriate.
Transient Side Effects
Lupron can cause several side effects that should resolve once the body becomes accustomed to its use. Symptoms experienced by both boys and girls can include acne, an increase in body odor, an increase in pubic hair, hot flashes, weight gain, mild body aches, mild headaches and drowsiness. Additionally, girls may experience short-term breast enlargement and short-term vaginal bleeding. If these symptoms persist, contact your pediatrician for further evaluation.
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