Seroquel XR is the extended-release version of the drug quetiapine. This medication is used in the treatment of schizophrenia and bipolar disorder. Because this drug affects the balance of chemicals in the brain, it has side effects that can range from mild to severe. If side effects are severe or persistent, a different dose of the drug or a change to a different drug may be necessary.
Gastrointestinal Effects
Like many other prescription drugs, Seroquel XR can affect the digestive system. According to Wolters Kluwer Health, the most common digestive system side effects of Seroquel XR are constipation and dry mouth. This drug can also cause an upset stomach and increased saliva production. These side effects may be relieved by taking Seroquel XR with food.
Cardiovascular Effects
Seroquel XR can affect the rhythm or rate of the heartbeat, so it's important to be aware of potential cardiovascular side effects. This drug can cause irregular heartbeat, fast heart rate and slow heart rate. These side effects are serious and should be reported to a medical professional.
Musculoskeletal Effects
This drug can cause side effects that impact the muscles, bones and joints of the body. Musculoskeletal system side effects of Seroquel XR include muscle weakness, stiffness, muscle pain and uncontrolled muscle movements.
Psychiatric Effects
Any drug that works to balance the chemicals in the brain can cause a wide range of psychiatric side effects, and Seroquel XR is no exception. Potential psychiatric side effects include agitation, depression, suicidal thoughts, hallucinations, hostility, aggressiveness, restlessness, irritability, panic attacks, trouble concentrating and suicidal actions.
Nervous System Effects
This drug can affect the nervous system in several ways. Seroquel XR can cause jerky movements or a loss of coordination. It may also cause dizziness, lightheadedness, drowsiness, fainting, confusion, memory loss, seizures, headache, numbness, tingling and twitching.
Allergic Reaction
Seroquel XR has the potential to cause an allergic reaction in anyone who is allergic to its ingredients. Symptoms of an allergic reaction include itching, hives, difficulty breathing, skin rash, swelling of the face and lips, tightness in the chest and swelling of the mouth and tongue. Seek immediate medical attention if a serious allergic reaction occurs.



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