Premarin is one of the brand names for the generic compound known as conjugated estrogens, according to EmedTV. The medication is available in a number of forms, including tablets and creams. It is used to restore hormone levels in menopausal women and some breast and prostate cancer patients, and replace estrogen in those who need additional amounts of the hormone to function normally, according to the Mayo Clinic. It produces several common side effects such as headache, nausea, stomach cramps and spotting, according to Drugs.com. However, the potential exists for more severe side effects which can include vision problems.
Increased Ocular Sensitivity
Drugs.com notes that one of the reported vision side effects of Premarin is an increased ocular sensitivity. This intolerance to contact lenses can force those taking the medication to seek alternative vision correction methods.
Vision Quality Changes
Changes in vision as a side effect of Premarin are considered to be one of the more serious side effects of the drug, notes EmedTV. These changes can be a side effect produced by the level of estrogen in the medication, according to MayoClinic.com, which also reports that sudden changes in vision are rare. The changes may be linked to other symptoms, or they may be a stand-alone phenomena. Any changes in vision should be reported immediately, notes MayoClinic.com.
Retinal Vascular Thrombosis
According to Drugs.com, use of Premarin preparations has been linked to increased incidence of retinal vascular thrombosis, also known as blood clots in the eye. These blood clots may be without symptoms, or they can cause the eyes to throb and bulge and make the patient's vision change suddenly. Patients who suspect that they are experiencing a blood clot in their eyes as a result of Premarin use should contact their health care provider immediately, as this is considered a very serious Premarin side effect.
Sudden Loss of Vision
EmedTV notes that one side effect of Premarin that is very serious is a sudden loss of vision. This loss of vision may be a side effect of the Premarin on its own as a result of the estrogen in its formulation, notes MayoClinic.com, or it may signal that a blood clot has developed in the eye. As one of the rare but serious side effects of Premarin, vision loss should be reported immediately to a doctor.



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