GERD or gastroesophgaeal reflux disease is esophageal mucosal damage produced by the abnormal backward flow of stomach contents into the esophagus. GERD can be treated with Nexium, a proton pump inhibitor that reduces the production of stomach acid. Still, some patients may experience GERD symptoms while taking Nexium. Such patients should seek medical attention because unrelieved symptoms while undergoing treatment are a sign of GERD complications, Mayoclinic.com notes.
Problems Swallowing
According to MayoClinic.com, some GERD patients who are being treated with Nexium may experience difficulties swallowing, or dsyphagia. Problems in swallowing are due to a narrowed esophagus caused by chronic injury to the esophagus. Chronic injury to the esophagus by stomach acid causes the esophagus to shorten and decrease in size. Painful swallowing may also be caused by candidiadiasis of the esophagus due to stomach acid suppression using Nexium. Stomach is important in killing fungus, and when it is suppressed for a long-time, fungus may grow in the esophagus.
Cancer of the Esophagus
According to eMedTV.com, patients may develop signs and symptoms of esophagus cancer while they are still taking Nexium. Esophageal cancer is a complication of GERD and occurs when cells on the lining of the esophagus change due to chronic exposure to stomach acid. Esophageal cancer is treatable when diagnosed early.
Asthma
According to MayoClinic.com, patients may develop asthma even when they are taking Nexium. Asthma symptoms occur when refluxed stomach contents cause injury to the trachea and bronchial tubes, leading to the inflammation of the airways. Patients experience wheezing, chest tightness and frequent coughing. Patients should elevate the head of the bed while sleeping in order to prevent refluxed stomach acid from entering the airways.
