Physicians may prescribe a medical form of the female hormone estrogen for a variety of reasons. In the case of the medication sold with the brand name Estring, the drug is used to treat several vaginal maladies by means of a cream, insert or suppository. MayoClinic.com reports that Estring may help women suffering from vulvar atrophy, vaginal inflammation or other problems. This medicine may be used in postmenopausal women who need the extra estrogen to balance their bodies, or it may be used in younger women who suffer from a lack of estrogen.
Swelling
The use of Estring may cause some swelling in various body areas as non-serious side effects. The hormone replacement therapy can cause the woman to experience swelling in her breasts, for example, Drugs.com indicates. She may feel tenderness or pain in her breasts, as well. She also may discover she has swelling in her feet and in her ankles while taking the medication, Drugs.com reports. These side effects do not constitute serious problems, but Drugs.com says the woman should seek advice from her doctor if these effects occur and do not go away or appear severe.
Sexual Difficulties
Taking Estring may cause the woman to experience changes in her sexual activities. She may, for example, find it difficult to reach an orgasm. She also may feel less interested in participating in sexual activities when she first uses Estring. These side effects also typically disappear as the woman continues to use the medication, but she should consult the doctor if they do not.
Depression
The introduction of extra estrogen into a woman's body can affect her mood. She may, while first using Estring, find she feels sad and empty. She may feel in a low mood and experience a sense of hopelessness. Depression may occur, primarily during initial use of Estring, Drugs.com indicates. Estring also may cause a state of irritability, MedlinePlus reports. These mental problems should stop without medical intervention. If they don't, the woman should question her physician or gynecologist about them.
Vaginal Problems
While Estring should serve to solve some of the vaginal problems associated with menopause such as discomfort, dryness and pain, it also can induce the conditions as side effects at the start of use. The medication also can cause the woman to produce a discharge from the vagina, MedlinePlus reports. Vaginal side effects typically occur in a mild form and should cease without help from a doctor.
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