Depression can influence emotional state, mood and the physical body. According to the Substance Abuse and Mental Health Services Administration, or SAMSHA, depression affects approximately 18.8 million American adults. SAMSHA explains that depression is characterized by feelings of hopelessness or sadness, loss of interest in pleasurable activities, decreased sense of self-worth, and changes in sleep, appetite, energy and concentration.
Physical Symptoms
"Arthritis Today," a publication of the American Arthritis Association, says physical symptoms of depression can resemble arthritis. Additionally, depression can exacerbate arthritis pain. Dr. Madhukar Trivedi says many people with depression only, or primarily, experience physical symptoms.
Diagnosis
Because many people visit their doctors for the physical symptoms of depression, the doctor may not recognize that depression is the cause of the discomfort. Furthermore, Trivedi says the more physical symptoms a person has, the more likely a mood disorder is involved. Patients who visit their doctors with physical symptoms can ask the doctor to rule out depression.
Treatment
According to Trivedi, antidepressants that affect both serotonin and norepinephrine, such as venlafaxine and duloxetine, have been effective in treating depression with physical symptoms. In conjunction with medication, psychotherapy, exercise and a healthy diet can help alleviate depression.


