Tamoxifen is a drug that is commonly used to treat breast cancers that require estrogen to grow. Also known as Nolvadex, Tamoxifen blocks the action of estrogen in the body, which in turn can prevent the growth and spread of breast cancer tumors. As with any medication, there can be side effects from the use of Tamoxifen.
Common Side Effects
There are several common side effects from the use of Tamoxifen that do not usually require medical attention. The most common ones are related to menopausal symptoms and include hot flashes, vaginal dryness, depression and mood swings, and decreased sex drive or impotence. Other common side effects, as listed by the National Cancer Institute, are headaches, nausea, vomiting, fatigue and skin rashes, including the skin area around the vaginal opening.
Serious Side Effects
There are some more serious side effects of Tamoxifen, although they are rare when compared to the occurrence of the more common ones listed above. These serious side effects include chest pain, a cough or vomiting that produces blood, bruising or pale skin, chest pain, pain or swelling in the legs and pelvic area, vaginal bleeding or irregular periods, dark urine or light, clay-colored stools and flu symptoms. Another very serious side effect that is reported with the use of Tamoxifen is the development of blood clots. If you experience a sudden headache, confusion, numbness or weakness on one side of the body or vision and speech problems, this could be the result of a blood clot or stroke. Seek medical attention immediately if you experience any of the symptoms listed above when using Tamoxifen.
Rare Side Effects
The American Cancer Society reports that there is rare, but extremely serious, side effect possible from Tamoxifen. This is the development of endometrial cancer and/or uterine cancer. Endometrial cancer occurs in the endometrium, which is the lining of the uterus. Uterine cancer occurs in the tissues of the uterus, and is also referred to as uterine sarcoma. The risk of these cancers is higher in postmenopausal women.
