Orlistat is the generic name for the weight loss drug marketed as Alli or Xenical, according to Drugs.com. RxList notes that Orlistat works as a lipase inhibitor, meaning that it interferes with the body's ability to absorb fat, causing weight loss. Orlistat is generally prescribed only to those who are already obese or overweight in order to help them drop pounds. Side effects do exist, specifically for the body's blood supply.
Jaundice
Orlistat's side effects on the blood in the body can lead to jaundice-like symptoms, notes MedlinePlus, a service of the National Institutes of Health. Signs of this side effect include a yellowing of the skin or the eyes. This may be an early sign of kidney and liver problems being caused by orlistat. As orlistat has been linked to severe kidney failure in some patients, this side effect on the blood is considered to be a very serious one that merits immediate medical attention.
Changes in Blood Nutrient Levels
Drugs.com notes that orlistat is not recommended for patients who are already struggling to get enough nutrients into their blood. Patients who have existing malabsorption syndrome should not take orlistat as it is intentionally designed to prevent the body from absorbing fatty materials, which can include fat soluble vitamins.
To offset this potential side effect of orlistat on blood nutrient levels, Patient UK and RxList note that patients may wish to take vitamin supplements while they are taking a course of orlistat treatments.
Reduction in Blood Sugar Levels
Orlistat can reduce the levels of blood sugar in patients. While this is beneficial for some patients, Drugs.com notes that patients who have diabetes or are receiving medication for diabetes-like symptoms may need to have their insulin or meds monitored to ensuring that an optimal dose is being received of both orlistat and the diabetic medication.
Changes in Blood Thickness
MedlinePlus notes that patients taking orlistat need to be mindful of its potential side effects on blood thickness. Individuals who are taking blood thinners or blood pressure medications may need to have their dosages changed when they start taking orlistat to modulate this side effect.
