Genacol, more completely known as Genacol Maximum Strength Cold & Flu, is the branded name for the generic compound of acetaminophen, chlorpheniramine, dextromethorphan and pseudoephedrine. It is commonly used to treat cold, flu and allergy symptoms, and is available over the counter as well as by prescription. The compound ingredients, however, can cause side effects.
Nausea or Vomiting
One side effect of Genacol is nausea or vomiting in patients. This may be caused by the acetaminophen in the Genacol, notes Drugs.com, as early signs of an acetaminophen overdose include nausea and vomiting. A low fever combined with nausea and vomiting may also be a sign of an allergic reaction.
Drowsiness
Multiple ingredients in Genacol are known to cause drowsiness. Drugs.com notes that both the dextromethorphan and the chlorpheniramine in the medication have the potential to make patients drowsy.
Allergic Reactions
Genacol has been linked to allergic reactions as a side effect in some users. Signs of an allergic reaction to Genacol can include warm and tingling skin, facial swelling, difficulty breathing, itching, and hives. A low fever with stomach upset may be a sign of a serious reaction requiring emergency care.
Incorrect Urinary Glucose Test Results
The acetaminophen in Genacol can alter urinary glucose test results. Drugs.com notes that diabetics who take Genacol will want to monitor their test results for false results while they are taking the medication.
MAO Inhibitor Interactions
Genacol carries a serious warning about potentially fatal side effects if it is combined with MAO inhibitors according to Drugs.com. This is caused by reactions to the dextromethorphan in the medication. The last dose of MAO inhibitor needs to have been at least two weeks prior to the start of Genacol treatment, or patients need to be tested to ensure the MAO inhibitor is out of their system.
Liver Damage
According to Drugs.com, one of the more serious potential Genacol side effects is liver damage. This is caused by the acetaminophen in the Genacol, which is known to damage the liver, especially in high doses. A high dose is more than 4,000 mcg per day, according to Drugs.com. Patients already facing liver challenges may not want to take the medication without a doctor's express permission.
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