The Effects of Long-Term Use of Tegretol

The Effects of Long-Term Use of Tegretol
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According to MayoClinic.com, Tegretol is a medication used to treat seizures in patients with epilepsy. The generic name for this medication is carbamazepine. This medication may also be prescribed to treat pain related to trigeminal neuralgia. Tegretol has been shown to calm the activity of nerves in the brain, which helps prevent epileptic seizures. Although an effective medication, Tegretol has serious side effects that may be experienced over the long term.

Bone Marrow Suppression

Tegretol may suppress the bone marrow, according to Drugs.com. This medication has been shown to decrease platelet or white blood cell counts when taken over the long term. Therefore, a patient is at a higher risk of excessive bleeding and increased infections. Although listed as a serious side effect, Drugs.com reports that only six patients per one million experience bone marrow suppression. However, regular blood tests are taken by the physician to assess this side effect.

Fatal Skin Reactions

MayoClinic.com states that certain patients have a genetic predisposition to having a fatal skin reaction when taking Tegretol. This serious reaction is more likely to occur in countries with mainly Caucasian populations, states Drugs.com. Researchers have found an association between this side effect and a specific gene type. However, patients without a specific genetic predisposition are less likely to experience a fatal dermatological reaction. If a patient does experience a significant reaction, he should seek emergency medical treatment.

Suicidal Thoughts

According to Drugs.com, a patient taking Tegretol is at an increased risk of having suicidal thoughts or behavior. This occurs because this medication may alter chemical signals in the brain that may be related to depression. A doctor should be consulted if such effects are experienced.

References

Article reviewed by Leah Ann Crussell Last updated on: May 8, 2011

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