Nystatin is an antifungal drug that is used to treat candida infections of the skin, mouth, vagina and the intestinal tract. It is available in dry powder, lozenge, tablet, suspension and ointment form. Nystatin is only available by prescription and, as with any antibiotic, it is important to follow the directions of the physician and complete the full course of treatment. Nystatin is generally well tolerated, and side effects are mild.
Gastric Disturbances
When taken orally, nystatin is absorbed in the mouth and not in the stomach. Very low levels of the drug are seen in the blood, and most of the oral nystatin is passed unchanged through the stool. This unabsorbed nystatin may cause gastrointestinal problems such as nausea, vomiting, stomach pain and diarrhea. According to MedlinePlus, gastrointestinal side effects are the most common with nystatin, and a doctor should be contacted if these symptoms persist or become worse.
Skin Reactions
Nystatin ointment is used to treat skin and vaginal candida infections and may provide immediate relief within 24 to 72 hours. Nystatin is safe to use and, as per information published on Drugs.com, it is well tolerated by all age groups, even during long-term use. In rare cases, a patient may experience itching, irritation and burning at the site of application. Most reactions are mild and may go away within a day. However, it is important to talk to a physician if the symptoms persist or worsen.
Allergic Reactions
According to Daily Med, a public service provided by the National Library of Medicine, only 0.1 percent of patients taking nystatin experience side effects. However, allergic reactions are more common and may manifest as a burning and itchy skin rash and eczema. Patients may also experience difficulty breathing and in closing of the throat, swelling of face and hives. In rare cases, patients may feel pain when applying nystatin ointment on the skin or vagina. If any of these reactions appear, the use of nystatin should immediately be discontinued, and emergency medical help should be sought, as some of these conditions may be life threatening.
