Salazopyrin is a prescription medication that contains the active ingredient sulfasalazine. It is indicated to treat certain inflammatory conditions, including inflammatory bowel disease and rheumatoid arthritis. This medication can be administered orally as a tablet, or rectally as a suppository or an enema. Patients should be aware of the side effects of Salazopyrin before beginning treatment with this medication.
Upset Stomach
Patients receiving treatment with Salazopyrin may experience stomach upset side effects, including vomiting or diminished appetite, according to MedlinePlus. Additionally, urgent, frequent bowel movements, also called diarrhea, may occur and can contribute to abdominal discomfort, cramping or pain.
Urine or Skin Discoloration
While taking Salazopyrin, patients may notice that their urine or skin appears an unusual yellow-orange color. This side effect is normal, does not require medical evaluation and will resolve once treatment with this medication ends.
Increased Sensitivity to Sunlight
Patients may experience increased skin sensitivity to sunlight that can increase the risk of sunburn upon exposure to sunlight. Whenever possible, patients should avoid direct exposure to sunlight while taking Salazopyrin by wearing protective clothing and applying sunblock to exposed skin, Drugs.com advises. Patients who develop a severe skin reaction after spending time in the sun should consult a medical professional for further evaluation and care.
Flulike Symptoms
Salazopyrin may cause flu-like side effects that may include fever, headache, sore throat, tiredness, weakness, or muscle or joint pain, notes MedlinePlus. Affected patients should seek care from a doctor as these side effects of Salazopyrin may be indicative of an alternate medical problem, such as an infection.
Temporary Male Infertility
Sulfasalazine, the active ingredient in Salazopyrin, may cause infertility in male patients, according to MedlinePlus. Male infertility is a condition characterized by the inability to impregnate a woman of reproductive age. This side effect of treatment is temporary and resolves once use of this medication ends.
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