Triphasil-28 is an oral contraceptive, or birth control pill, manufactured by Pfizer. Some women should not take this medication due to the potential for life-threatening side effects. Women diagnosed with heart or lung disease, who smoke or who have cancer should not use this oral hormone, according to MedlinePlus. A myriad of side effects have been associated with Triphasil-28 use and should be reported to a health care provider.
Hormonal Changes
Some of Triphasil-28 side effects stem from the two hormones in the pill, ethinyl estradiol and levonorgestrel, which are forms of estrogen and progestin that work together to mediate the menstrual cycle and stop ovulation. These hormones can cause hair loss, weight changes and breast pain and swelling. Spotting, or mid-cycle bleeding, is also a side effect of Triphasil-28.
Cardiovascular Effects
Triphasil-28 has a direct cardiovascular impact inclusive of the heart and circulatory system. Serious side effects of taking Triphasil-28 include heart attack, stroke and blood clots. The occurrence of these side effects drastically increase for women who smoke cigarettes or are older than 35. Chest pain, one-sided weakness or numbing of the body or confusion may signify a life-threatening side effect and must be treated immediately.
Liver Damage
Triphasil-28 can induce serious side effects in the liver. Jaundice, or a yellowish color to the skin and eyes, dark urine and abdominal pain are reflective of liver damage. MedlinePlus relates that these oral contraceptives are known to create non-cancerous tumors within the liver that may erupt and bleed. The patient information section of Pfizer's Triphasil-28 instructions cites some instances of breast and liver cancer.



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