Proton pump inhibitors, or PPIs, are a group of drugs that work by reducing the production of acid by cells that line the stomach. PPIs include brand name medications that are commonly available by prescription only such as Nexium, Aciphex and Dexilant. Drugs.com notes that these medications cannot give immediate relief from heartburn and acid reflux. They are also powerful drugs that are not recommended for occasional heartburn, but are used to treat chronic gastroesophageal reflux disease, or GERD. In the U.S. there is a PPI medication called Prilosec that is available without a prescription. This and other over-the-counter brands are taken in the same way as the prescription brands. As with all medications, PPIs can cause adverse effects and should be taken as recommended only.
Step 1
Read the detailed instructions on the prescription or over-the-counter proton pump inhibitor before taking the medication.
Step 2
Take one tablet, or the dosage instructed, at the same time everyday. Proton pump inhibitor medications cannot relieve acid reflux symptoms right away. They will affect symptoms approximately a week after taking them regularly.
Step 3
Swallow the tablet with a full glass of water. Proton pump inhibitors are usually not taken with food.
Step 4
Take the proton pump inhibitors until they are finished as advised by your doctor. If symptoms of heart burn persist, consult the prescribing doctor for further treatment. If there are refills, begin the second dosage.
Tips and Warnings
- Proton pump inhibitors are a preventative medication for long-term relief of heartburn due to GERD. The prescribed dosage should be completed for results.
- Do not take more medication than prescribed or for longer durations than recommended. Proton pump inhibitors can cause adverse side effects if taken for longer periods than advised. Pregnant and nursing women should not take this medication without the advice of their doctor.
Things You'll Need
- Proton pump inhibitor oral medication
- Glass or cup
- Water or drink


