Tylenol PM is an over-the-counter medication indicated to alleviate sleeplessness and mild to moderate body or head pain. This medication contains two active ingredients: diphenhydramine, an antihistamine and sleep aid; and acetaminophen, a pain and fever reducer. Before taking this medication, people should be aware of the potentially bad side effects of Tylenol PM.
Oral or Nasal Dryness
Treatment with Tylenol PM may cause oral or nasal dryness in certain people, Drugs.com reports. These side effects may lead to dry mouth, a sore throat, increased thirst, nasal irritation or sneezing.
Stomach Upset
After taking a dose of Tylenol PM, certain people may develop stomach upset side effects due to the presence of diphenhydramine in this medication. Nausea or vomiting can occur, which may lead to a temporary decrease in appetite. Certain people may also experience constipation, or difficult bowel movements, in conjunction with nausea or vomiting, MedlinePlus reports.
Drowsiness or Excitability
Diphenhydramine may induce drowsiness or sleepiness in people who take Tylenol PM. This medication should only be taken immediately before a person intends to go to sleep. Use of this medication in conjunction with driving or participating in hazardous activities can significantly increase a person's risk of sustaining or causing injury or harm. In certain people, such as children, this medication may cause unusual excitability, which may make it difficult for them to fall asleep or stay asleep during the night, Drugs.com warns.
Dizziness or Blurred Vision
Unusual sensations of lightheadedness or dizziness may arise in people treated with Tylenol PM. Blurred or cloudy vision changes may also develop, which can exacerbate dizziness episodes. People who experience severe dizziness in conjunction with confusion, restlessness or hallucinations while taking Tylenol PM should seek prompt care from a medical professional, Drugs.com advises. Such side effects may indicate a severe reaction to this medication.
Tinnitus or Headache
Abnormal buzzing or ringing sounds may develop in a person's ears after treatment with Tylenol PM. This side effect, called tinnitus, may be bothersome and can result in headache pain or discomfort in affected people.



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