Vitamin B6, also called pyridoxine, works in the body to create myelin, hemoglobin and to synthesize norepinephrine and serotonin. An adequate supply of B6 is needed to keep blood cells, mucous membranes, skin, and the peripheral nerves healthy, notes MedlinePlus. Most multivitamins contain B6. There are some side effects reported from the intake of vitamin B6.
Nerve Damage
Vitamin B6 can also cause damage to the nerves in the upper and lower limbs. This damage will be reversible once the overly high dose of B6 is stopped, notes the National Institutes of Health. A doctor should be notified immediately about any unusual numbness or tingling in the limbs that could be related to nerve damage.
Breast Tenderness and Enlargement
Breast tenderness or an increase in size can occur during the time when B6 supplements are taken, notes MedlinePlus. This effect can cause pain that can limit activities such as exercise or lifting objects. If the breast tenderness is problematic during daily activities, a doctor should be alerted.
Photosensitivity
Photosensitivity can occur due to the intake of Vitamin B6, notes MedlinePlus. This symptom can cause the skin to become very sensitive to the sun. A doctor should be asked about the necessity of limiting all sun exposure during B6 treatments.
Seizures
Seizures can occur with high doses of B6, notes MedlinePlus. This serious symptom requires immediate care by a doctor. Extra B6 should never be taken without a doctor's approval and all label directions should be followed.
Pain and Vomiting
Stomach pain, headache, nausea, vomiting and lack of appetite can occur during B6 treatments, notes MedlinePlus. These symptoms can be ongoing or just appear sporadically. A doctor should be notified if the nausea, vomiting, lack of appetite or pain are interfering with daily activities.



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