Clindesse is a prescription medication that contains the active ingredient clindamycin, a type of antibacterial medication. On January 28, 2009, Ther-Rx Corporation, the manufacturer of this medication, initiated a voluntary recall of Clindesse due to sub-par manufacturing techniques utilized during production of this product. Clindesse is indicated to treat bacterial vaginosis, a type of vaginal infection in women characterized by unusual, foul-smelling vaginal discharge and vaginal irritation. This vaginal cream is administered directly into the vagina using an applicator or plunger. Women should discuss the side effects of Clindesse with a medical professional before using this medication.
Vaginal Yeast Infection
Treatment with this medication can disrupt the normal balance of bacteria present in a woman's vagina. If this occurs, a certain type of fungus, called Candida albicans, may rapidly reproduce in the vagina, leading to a vaginal yeast infection. During clinical trials for Clindesse, approximately 14 percent of women reported developing a vaginal yeast infection, according to Ther-Rx Corporation. Symptoms of a vaginal yeast infection include intense vaginal itching or irritation accompanied by thick, white, clumpy vaginal discharge. Women who develop this side effect after using Clindesse should consult a doctor. Additional antifungal medication is typically necessary to eradicate the fungal infection and alleviate uncomfortable vaginal symptoms.
Headache
Painful headache symptoms may emerge in certain women who use Clindesse. Headache discomfort can be bothersome and may interfere with a woman's ability to remain alert or focused during daily activities. If headache pain is disruptive, affected women can take an over-the-counter pain medication to help alleviate head discomfort.
Upset Stomach
After using Clindesse, certain women may experience upset stomach side effects, such as nausea. Women may also experience a frequent urge to have a bowel movement, or diarrhea, which may occur in conjunction with stomach pain or cramping, Drugs.com warns. If women notice blood or mucus within their stools, they should seek prompt care from a medical professional.



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