Comtrex is an over-the-counter medication indicated to alleviate symptoms associated with a sinus infection or the common cold. This medication contains three active ingredients: acetaminophen, a pain- and fever-reducing medication; pseudoephedrine, a nasal decongestant; and dextromethorphan, a cough suppressant. Before taking this medication, people should be aware of the side effects of Comtrex.
Restlessness or Insomnia
People who take Comtrex may become unusually restless or nervous as a side effect of treatment, Drugs.com warns. Increased excitability may interfere with a person's ability to sleep through the night, which is a side effect of Comtrex called insomnia. People who experience insomnia may also become more tired during the day, which can disrupt their ability to remain alert and active during normal activities.
Unusual Skin Sensations
Comtrex may cause unusual skin sensations, such as warmth or tingling, in certain people. This side effect of treatment may also occur in conjunction with the appearance of a red, irritated skin rash. People who develop uncomfortable skin sensations, such as numbness, in addition to chest pain or vision problems should seek prompt care from a medical professional.
Upset Stomach
Following treatment with this medication, people may experience upset stomach side effects, such as nausea, RxList reports. Stomach discomfort may also lead to a temporary decrease in appetite in certain people. People who experience these stomach-related side effects in conjunction with yellow skin discoloration or abnormally colored urine or stools should consult a doctor as soon as possible. These side effects may be signs of liver damage.
Headache, Dizziness or Drowsiness
Head pain, dizziness or drowsiness may develop in people receiving treatment with Comtrex. People who experience dizziness or lightheadedness may have difficulty remaining stable while standing, or may appear disoriented or confused. Head pain or increased fatigue may also make it difficult for people to remain attentive or focused during daily activities.
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