Statin drugs are cholesterol-lowering medications that block a chemical in the body that creates cholesterol. They also help the body to reabsorb built-up cholesterol plaque in the artery walls, preventing further blockage from occurring, according to MayoClinic.com. There are several well-known statin drugs doctors prescribe for high-cholesterol levels. They can prevent both heart attacks and strokes, especially for those with a family history of cardiovascular disease. Statin drugs have a number of ingredients helpful in propagating its function.
Atorvastatin Calcium in Lipitor
Atorvastatin calcium is an insoluble white to off-white crystalline powder present in the synthetic lipid-lowering agent of the common statin drug, Lipitor. It functions as an inhibitor of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, according to RX List. It helps to reduce the multiple risk factor of increased atherosclerotic vascular disease and works optimally when combined with a healthy food and exercise regimen. Multiple risk factors include age, smoking, hypertension and a family history of early coronary disease. Inactive ingredients include calcium carbonate, candelilla wax, magnesium stearate, lactose monohydrate, micro-crystalline cellulose and other compounds that help facilitate and preserve the functionality of the atrorvastatin calcium in Lipitor to reduce high cholesterol levels.
Simvastatin in Zocor
Simvastatin in Zocor is synthetically derived by fermenting Asperigillus terreus for oral ingestion, according to the website RX List. It is a white to off-white, non-hygroscopic, insoluble crystalline powder. It acts by hydrolyzing into a beta hydroxyacid form, which is actually an inhibitor of cholesterol synthesis. This effectively lowers cholesterol levels in those taking the drug. Inactive ingredients include ascorbic acid, citric acid, hydroxypropyl cellulose, iron oxides, lactose and magnesium stearate among others for complete function. Simvastatin includes butylated hydroxyanisole as a preservative.
Lovastatin in Mevacor
Lovastatin, like other fellow statins, lowers the risk of stroke, heart attack and other heart complications in individuals with diabetes, coronary heart disease and other risk factors, including family history and lifestyle. It works by reducing levels of "bad" cholesterol while increasing the levels of high-density lipoprotein, or HDL, known as "good" cholesterol, according to Drugs.com. Inactive ingredients include cellulose, lactose, magnesium stearate and starch. BHA, or butylated hydroxyanisole, is used as preservatives to ensure longevity and function, RX List states. Lovastatin is available in oral form and is available in either 20 mg or 40 mg dosages.
