Sunitinib malate is a medication that is used in the treatment of certain cancers such as gastrointestinal stromal tumors and advanced renal cell cancer, according to OncoLink.org. Sunitinib is a targeted therapy; these medications work by targeting a specific substance or target in cancer cells, which means that healthy cells are less likely to be affected. Although sunitinib impacts mostly cancer cells, patients may still experience some side effects while taking this therapy.
Diarrhea
Like many types of cancer medications, sunitinib malate can cause diarrhea in the patients who take it, according to Chemocare.com. This side effect typically occurs in more than 30 percent of patients. A patient should let the doctor know if this side effect occurs as soon as possible. The physician may prescribe a medication or a change in diet to help manage the situation.
Nausea and Vomiting
Another potential side effect of sunitinib malate is nausea and vomiting, according to OncoLink.org. The physician can prescribe medication for nausea and vomiting; patients may also lessen the symptoms by eating a small meal before treatment. Patients should also let the physician know about this symptom to ensure that the symptom does not become too severe.
Loss of Appetite
Patients taking sunitinib may also lose their appetites, according to the NetDoctor, a United Kingdom information website. Patients can take steps to make sure that the foods that are consumed maintain the appropriate calorie intake. A loss of appetite should be reported to the physician as soon as possible.
High Blood Pressure
Patients taking sunitinib may develop high blood pressure, according to the MayoClinic.com. The physician or nurse should monitor the blood pressure during therapy; any high blood pressure should be treated as needed. Severe high blood pressure elevation might require a discontinuation of the medication until the blood pressure is better controlled. Patients with high blood pressure before therapy should use sunitinib with significant caution.
Low Blood Cell Counts
Sunitinib can also cause low blood cell counts, according to Chemocare.com. White blood cells, red blood cells and platelets may all decrease while taking this medication. The patient may be more prone to catching infections; the patient may also become fatigued during the treatment. If the patient develops nosebleeds or bleeding gums, the nurse or doctor should be contacted for further evaluation.
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