Alli is an over-the-counter version of the weight-loss drug orlistat. Alli contains 60mg of orlistat, in contrast to the prescription form, Xenical, that contains 120mg. Manufactured by GlaxoSmithKline, Alli works by preventing absorption of some fat in your diet. Consult a qualified health care provider before taking Alli diet medicine.
Treatment Indication
Alli is intended as part of a comprehensive weight loss program that includes a reduced-calorie diet and exercise, as noted by the website Drugs.com. It is indicated for obese people who have additional health risk factors, such as high cholesterol, high triglycerides, high blood pressure or diabetes.
Function
Alli works by inhibiting the action of lipase, an enzyme that digests dietary fat. Lipase breaks down fat into smaller components for energy or storage for later use, explains the Mayo Clinic website. Since Alli prevents lipase from digesting a certain amount of the fat you eat, this fat continues through your intestines undigested until it is eliminated through bowel movements.
Usage
Use Alli as instructed on the package or follow your doctor's instructions. Take the medicine during or within one hour after a meal that includes some fat, usually breakfast, lunch and dinner. If you miss a meal, skip the Alli dose for that meal, advises Drugs.com. Avoid high-fat meals, which can lead to disagreeable side effects. While using Alli, your daily fat intake should be 30 percent or less of your total daily calories.
Side Effects
Intestinal side effects are likely with Alli, particularly if you eat more fat than recommended. These effects occur due to the fat-blocking properties of the medicine, and they should dissipate as you continue treatment, according to Drugs.com. Side effects may include oily or fatty bowel movements, gas with oily spotting, loose stools, increased frequency of bowel movements and an inability to control bowel movements.
Safety
The U.S. Food and Drug Administration has received rare reports of serious liver injury in people taking orlistat. Although no link has been established, seek medical attention if you take Alli and develop any symptoms of liver problems, such as fatigue, weakness, jaundice or dark urine.
Considerations
Research with orlistat has mainly focused on the prescription-strength version, notes MayoClinic.com. The average weight loss for people using Xenical in these studies is about 5 to 7 lbs. per year more than for people using diet and exercise alone.
Member Comments