Side Effects of Praziquantel

Praziquantel is sold under the brand name Biltricide in the United States, and according to Drugs.com, is commonly prescribed for the treatment of schistosome infections, as well as infections from liver fluke. The Mayo Clinic describes liver fluke infections as snail fever, bilharziasis or schistosomiasis. Praziquantel may also be prescribed for other worm infections, but is not effective for roundworms such as pinworms. The medication works by causing severe spasms as well as paralysis in the muscles of the infecting worms, which are then eliminated from the body through the stool.

Common Side Effects

Patients taking praziquantel commonly experience a variety of side effects that are bothersome but not health-threatening. The Mayo Clinic states that often these side effects dissipate as your body adjusts to praziquantel; if not your doctor may be able to give you information on reducing or eliminating these side effects. The most common side effects include bloody diarrhea, dizziness, drowsiness, stomach cramps or abdominal pain, headache, fever, loss of appetite, sweating, nausea, vomiting or a general feeling of discomfort.

Less Common Side Effects

Side effects that are not commonly seen with praziquantel use but are not life-threatening are hives, itching and skin rash. There have also been reports of praziquantel patients experiencing light-headedness or dizziness, loss of strength, drowsiness or sleepiness, a spinning sensation or a feeling of constant movement. While these incidences are attributed to praziquantel use, they have not been reported often enough to be classified as side effects.

Side Effects Requiring Medical Attention

If any of the following occur, you should contact your physician as soon as possible: feeling discomfort or pain in the chest or experiencing an irregular, slow or fast heartbeat. Additional side effects requiring medical attention are hoarseness, irritation, joint pain or swelling, seizures, shortness of breath or trouble breathing, severe abdominal pain, swelling of the hands, feet, lips or eyelids. Additionally, report continuing hives, rash or itchiness to your doctor.

References

Article reviewed by Elizabeth Ahders Last updated on: Feb 7, 2012

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