Cancer is the result of genetic mutations that cause cells within the body to grow and divide in an out of contro. Cancer is not the result of a single mutations but rather a series of mutations that build up over time. In the brain, glial cells are responsible for supporting and protecting the neurons. The most common form of primary brain cancer arises from these cells, forming gliomas. One form of glioma is called glioblastoma multiforme, also known as glioblastoma.
Identification
Gliomas are cancers that have their origins in glial cells. Gliomas can be separated into four stages based on how abnormal the cells are, with stage IV having the most abnormal cells. Glioblastoma multiforme describes a glioma that has dead tumor cells in the middle. It is a Stage IV brain cancer.
Incidence
Glioblastoma multiforme makes up approximately half of all glioma cases. They are most common in people between the age of 45 and 50, and men are more likely to get glioblastoma multiforme than women. Glioblastoma accounts for a little less than one in 10 childhood brain tumors.
Cause
Cancer is the result of genetic mutations that occur in the cell. Although most of these mutations occur at random, some are hereditary and may be passed down genetically. According to the American Brain Tumor Association, genetic changes on chromosomes 10 and 17 may predispose an individual to develop glioblastomas. Researchers are working to identify additional risk factors.
Symptoms
The growth of a brain tumor interferes with the brain's function. Symptoms of a glioblastoma are caused by this interference. The earliest symptoms of a glioblastoma are the result of increased pressure on the brain. This can cause memory loss, seizures, hallucinations and sudden changes in behavior.
Diagnosis and Treatment
Brain tumors are most typically diagnosed with an MRI or a CT scan. These scans may involve special dyes that help make the tumor easier to see. The first line of treatment for glioblastoma is surgical removal, if the tumor is in a location that is operable. Radiation treatment and chemotherapy are also commonly used to treat this form of brain cancer.
