Stanozolol is a synthetic steroid similar in structure to naturally occurring testosterone. It is indicated for the treatment of hereditary angioedema, or HAE. Stanozolol is classified as an anabolic-androgenic steroid; anabolic refers to tissue-building properties, while androgenic refers to promoting masculine effects. Stanozolol was approved by the Food and Drug Administration in 1962 and has been studied extensively in clinical trials and post-marketing research. Stanozolol has proven generally safe if taken as directed, but side effects may range from mild to serious.
Desired Effects
Stanozolol is effective at treating HAE. According to the US Hereditary Angioedema Association, HAE is a rare but serious disease that can result in major swelling of the extremities, face, upper airway, trunk and abdominal and genital regions. Hereditary angioedema is caused by a dysfunction in a plasma protein called the C1 inhibitor. In the September 2007 issue of "The Journal of Allergy and Clinical Immunology," Dr. David Sloane and associates report that stanozolol effectively increases the C1 inhibitor, thereby preventing spontaneous soft-tissue trauma caused by episodes of HAE. Sloane states that stanozolol is a safe and effective drug for the long-term and preventative treatment of HAE.
Side Effects
According to Drugs.com, patients may experience cardiovascular, sexual, liver, musculoskeletal, immune system, kidney, metabolism and gastrointestinal-related side effects. Common yet serious liver side effects are yellowing of the skin and eyes due to bile displacement, raised liver enzymes and inflammation that may lead to scarring. Female patients are especially susceptible to masculinizing effects. The study by Sloane and associates reported that the female study participants experienced increased body hair, menstrual irregularities, post-menopausal bleeding, acne and mood swings. Patients may also experience nausea and vomiting.
Warnings and Precautions
Stanozolol comes with several warnings and precautions. According to Drugs.com, patients should inform their physician before taking stanozolol if they have prostate cancer, breast cancer or hypercalcemia, a condition involving excessive levels of calcium in the blood. Patients should also inform their doctor first if they have a heart condition, blood clotting problems, diabetes and liver or kidney problems. Stanozolol carries a moderate potential for abuse, leading to physical and psychological dependence.
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