Amoxicillin Trihydrate and Clavulanate Potassium Side Effects

Amoxicillin trihydrate and clavulanate potassium are used in combination to treat certain types of bacterial infections, including sinus, ear and lung infections. This medication is typically administered orally twice daily or as recommended by a physician. Patients should talk with a doctor about amoxicillin trihydrate and clavulanate potassium side effects before beginning treatment with this combination of medications.

Diarrhea

In clinical trials for this medication, the most commonly reported side effect as diarrhea. Nearly 15 percent of patients experienced frequent bowel movement urges that yielded watery or loose stools, according to the FDA. Patients who develop diarrhea while taking amoxicillin trihydrate and clavulanate potassium may also experience abdominal cramping, bloating or discomfort. FDA health officials recommend patients take this medication after eating a meal to help reduce the risk of developing diarrhea. Severe diarrhea side effects, such as bloody stools, can be a sign of a potentially life-threatening reaction to this medication and affected patients should seek emergency medical care.

Nausea

Nausea side effects may arise following treatment with amoxicillin trihydrate and clavulanate potassium. An estimated 2 percent of patients became nauseous after receiving treatment with this medication during clinical trials, RxList reports. Nausea may also contribute to a temporary decrease in appetite and can occur in conjunction with diarrhea.

Hypersensitive Reaction

Use of this medication may induce severe hypersensitive reactions in certain patients, Drugs.com warns. Patients who exhibit symptoms of a hypersensitive reaction, including itching, swelling or skin rashes, should be evaluated by a medical professional immediately. Additional hypersensitive reactions may include flu-like symptoms, such as fever or muscle or joint aches. If left untreated, hypersensitive reactions can be fatal.

References

Article reviewed by Roman Tsivkin Last updated on: Oct 1, 2010

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