Celexa, or citalopram hydrobromide, is a medication that belongs to the selective serotonin-reuptake inhibitor class that is generally prescribed for the treatment of depression. Emerging research on newer drugs in this class, according to "Current Pharmaceutical Design," suggests that while the side effects are typically less problematic for this class overall, cardiovascular problems are considerable with their use. It is important to discuss all family and personal medical histories with the prescribing physician in order to make the best treatment decision.
Arrhythmias
Arrhythmias, or erratic heartbeats, can become quite common among those taking Celexa. According to "Current Pharmaceutical Design," Celexa use compromises potassium, sodium and calcium channel concentrations. These important electrolytes, when imbalanced, can cause the heart and other vital organs to stop functioning or shut down completely. Tachycardia is a condition comprised of an extremely fast heartbeat exceeding 100 beats per minute, or bpm. Providence Health and Services posits that tachycardia is an arrhythmia, where the heartbeats occur from short-circuiting in the electrical system of the heart.
Electrolytes, when out of balance, may disturb the heart's natural rhythm and normal pacing by increasing the rate and making it race abnormally. Tachycardia may become life-threatening and requires immediate medical attention. Celexa should not be discontinued except under the advisement and supervision of a licensed health professional.
Hypotension
Celexa has been linked to hypotension. Hypotension is a condition in which blood pressure actually dips too low. This usually makes an individual feel faint. The National Heart Lung and Blood Institute Diseases and Conditions Index states that hypotension can be indicated by other signs and symptoms such as dizziness, lightheadedness, blurred vision, confused mental state, weakness and possibly accompanying nausea. In some cases, sitting or reclining may increase blood flow in the body and decrease symptoms. The prescribing physician may change medications or adjust the dose to reduce hypotension.
Infrequent Effects
Celexa has been linked to other, less frequent heart conditions. Less common but possible cardiovascular effects caused by Celexa, according to RxList, include hypertension, bradycardia, edema, angina, extrasystoles, cardiac failure, flushing, myocardial infarction, cerebrovascular accident and myocardial ischemia. In one out of every 1000 patients taking this drug, these effects may be seen.
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