Hydrocort is a cream-based topical corticosteroid that is used to treat inflammatory or itching skin conditions. According to ADAM, the cream is available in prescription and nonprescription formulations. Hydrocort cream applications have been linked to a number of side effects in addition to relief of the primary ailment. In choosing to use Hydrocort, it is important to be aware of its side effects.
Skin Rash
Though Hydrocort is designed to provide relief from skin ailments, it may have the opposite effect. Skin rash is considered to be a less common side effect of products like Hydrocort cream that contain hydrocortisone, but it is still considered to be a serious side effect that should be immediately brought to a doctor's attention. Signs of a skin reaction to Hydrocort include a burning sensation followed with redness in the skin, scaling or crusted skin and scaly rashes, according to MayoClinic.com.
Skin Quality Changes
As a result of using Hydrocort, the quality of the skin may change. Drugs.com notes that these changes may include a lightening of the skin tone, the development of stretch marks or thinning of the skin. These skin quality side effects are considered to be less serious side effects of using Hydrocort cream. It is not necessary to discontinue use of Hydrocort where these skin quality changes occur, but Drugs.com notes that these side effects are more likely to occur with prolonged use.
Vision Changes
With long-term use of Hydrocort, more of the hydrocortisone in the cream will be absorbed into the body's system, leading to visual changes. According to Talk Medical, these changes may be minor or obvious, such as halos around lights or blurred vision. If these visual changes occur, Hydrocort should immediately be discontinued and a medical professional should be contacted.
Adrenal Gland Problems
According to ADAM, using Hydrocort has been linked to problems with the adrenal gland. Due to the presence of hydrocortisone, if the cream is used in excess over an extended period of time, the risk of developing adrenal gland issues will increase. This side effect is more likely to strike children as well as long-term users.



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