Daflon is a drug used to treat venous insufficiency, a condition in which oxygen-poor blood is not adequately pumped back to the heart. Venous insufficiency is characterized by varicose veins, leg swelling, skin irritation and ulcers. A review article in the journal "Drugs" reports that several clinical trial studies have demonstrated that Daflon is effective for treating chronic venous insufficiency. Daflon is a combination of plant flavonoids, and there are few reports of side effects associated with its use.
Gastrointestinal Disturbances
A review of the safety of Daflon in the journal "Angiology" reports that gastrointestinal side effects were reported in 10 percent of those treated with Daflon in clinical trials, although the incidence of gastrointestinal disturbances was actually lower than in participants who received placebos in these trials.
Colitis
One case of colitis associated with Daflon therapy was reported in the French journal, "Gastroenterologie Clinique et Biologique." Colitis is a condition in which the colon is inflamed, causing symptoms of diarrhea, abdominal pain and cramping.
Mild Palpitation
A multicenter study published in the "Journal of the Royal College of Surgeons Edinburgh" reported one case of mild palpitation, or irregular heartbeat, in a person treated with Daflon.
References
- "Drugs"; Micronised Purified Flavonoid Fraction: A Review of Its Use in Chronic Venous Insufficiency, Venous Ulcers and Haemorrhoids; K.A. Lyseng-Williamson and C.M. Perry; 2003
- "Angiology"; Safety and Security of Daflon 500 mg in Venous Insufficiency and in Hemorrhoidal Disease; O.C. Meyer; June 1994
- "Journal of the Royal College of Surgeons Edinburgh"; Daflon for Haemorrhoids: A Prospective, Multi-centre Observational Study; A-W. N. Meshikhes; December 2004
- "Gastroenterologie Clinique et Biologique"; Chronic Diarrhea and Lymphocytic Colitis Associated with Daflon Therapy; D. Mennecier et al.; October 1999
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