Yeast, fish, meat, green vegetables, cereals and beans contain niacin, a form of vitamin B3, necessary for the normal functioning of the digestive system, skin and nerves. Medline Plus reports that as a water-soluble vitamin, it assists in the conversion of food to energy sources that the body can use. While niacin can result in beneficial side effects, it can also result in negative side effects.
Preventing the Development of Pellegra
Niacin deficiency can result in a severe condition known as pellegra. The University of Maryland Medical Center describes pellegra as a condition with signs such as cracked, scaly skin, dementia and diarrhea. Pellegra occurs from compromised intake of niacin due to poor nutrition and alcoholism or the compromised ability to absorb niacin, usually seen in malabsorptive states. Prolonged diarrhea and altered metabolism affecting niacin synthesis, seen in patients having fad diets, anti-tuberculosis therapy and cancer tumors, may also result in pellegra. Management of pellegra requires niacin supplements and withdrawal from the offending risk factor.
Reducing Cholesterol Levels
According to a statement released by the University of Maryland Medical Center, Niacin reduces bad cholesterol levels in the blood. This ultimately results in reducing the development of atherosclerosis and in the prevention of heart related problems. According to Medline Plus, niacin prescribed in doses of 500mg or higher may reduce cholesterol and prevent heart disease.
Reducing Liver Damage
According to the University of Maryland Medical Center, some patients on high daily doses of niacin to control cholesterol might incur liver damage. The cause is unknown. Regular monitoring of the liver function helps in preventing the development of liver disease and damage.
Skin Change
Niacin supplementation commonly causes skin flushing. Medline Plus enumerates that flushing usually causes burning, tingling and redness of the face, arms and chest. The side effect usually resolves when patients stop using niacin. Alcohol consumption can worsen skin flushing and avoiding alcohol helps prevent this side effect.
References
- Medline Plus: Niacin and Niacinamide (Vitamin B3)
- University of Maryland Medical Center: Vitamin B3 (Niacin)
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