Malaria is a serious disease caused by infection by blood parasites from the Plasmodium family. Malaria is major concern in tropical parts of the world because it is spread via the bites of contaminated mosquitoes, which thrive in the warm and humid climates of the tropics. Mefliam is a medication that can be used to either treat or prevent malaria, but there are some serious side effects associated with its use.
Upset Stomach
Because Mefliam is taken orally, it can cause an upset stomach. This can result in abdominal pain, nausea, vomiting and diarrhea. The symptoms of an upset stomach caused by Mefliam are generally fairly mild and may decrease or go away on their own even if the patient continues to take the medication. An upset stomach is one of the most common side effects associated with Mefliam and occurs in approximately 3 percent of patients who take the medication.
Vestibular Dysfunction
The human body's sense of balance is controlled by the vestibular system, which is located in the inner ear. Mefliam can cause some disruption of this system, resulting in problems with balance or dizziness. Trouble with balance can cause patients to develop an abnormal gait or to be prone to falling. The dizziness and balance difficulties can continue for months after the patient has stopped taking the medication. Although problems with the vestibular system occur in less than 1 percent of patients, these side effects are still among the most common of those observed with Mefliam, particularly in patients taking the medication for malaria prevention. Sometimes Mefliam may also cause ringing in the ears, also known as tinnitus.
Flu-Like Symptoms
Mefliam can also generate symptoms which are similar to those caused by influenza. These include a fever, chills and muscle aches. Although these side effects can cause discomfort, they generally are not serious and disappear when the patient stops taking the medication.
Cardiac Arrhythmia
One of the more serious side effects of Mefliam is cardiac arrhythmias. The most common arrhythmia associated with Mefliam is extrasystole. With extrasystole, the heart occasionally contracts before its chambers are fully filled with blood, which can make the heart pump less effectively. More severe arrhythmias are also possible, however, and can cause heart palpitations and changes in heart rate.
Sleep Disturbances
Mefliam can also cause some changes in a person's sleeping habits. Some people will become unusually drowsy while taking Mefliam. Others may experience insomnia or have abnormal dreams.
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