About Rebif

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Overview

Rebif or interferon beta-1a is an injectible prescription drug made from protein that is similar to the amino acids of human interferon produced in the body. Refib is effective in fighting viral infections and in treating the relapse symptoms of multiple sclerosis. Multiple sclerosis is an auto-immune disease. Meaning your own immune system damages your body causing scar tissue buildup in multiple areas of your central nervous system (brain and spinal cord). According to the National MS Society, multiple sclerosis affects approximately 400,000 Americans and about 2.5 million people world.

Function

According to Msaustralia.org, clinical trials found that Rebif (interferon beta-1a) has a significant effect in people with relapsing, remitting multiple sclerosis by reducing the accumulation of permanent physical disability. Refib helps to regulate the immune system and decreases the attacks on myelin (protective layer around the nerves) or nerves. Refib is available in a pre-filled, pre-measured, prescribed dosage and is given subcutaneously (under the skin).

Benefits

Rebif is an effective treatment for multiple sclerosis. However it is not a cure. Refib will work to slow down the progress of the disease and it will decrease the frequency of relapsing multiple sclerosis. It will ease the symptoms such as fatigue, headache and depression or tremors among others.

Side Effects

The side effects of Rebif may include symptoms of an allergic reaction such as a rash or hives with itching along with swelling of the face, tongue and throat or shortness of breath or difficulty breathing. This is a serious medical emergency. Get immediate emergency medical care and attention if you should experience any of these symptoms.

Other symptoms may include headache, nausea and stomach pain as well as redness, pain or swelling and tenderness at the injection site. There may also be a runny or stuffy nose along with a feeling of depression, anxiety and insomnia, restlessness or thoughts of hurting yourself.

Discussion with Your Healthcare Provider

Discuss your medical history with your doctor and any medications your are taking, including herbal products or over the counter drugs and any allergies you may have. Inform your doctor if you have had a history of thyroid problems, liver diseases, seizures or depression. Inform your doctor if you are pregnant, breast feeding or planning to get before taking Rebif.

Warning

Avoid being in contact with others who are sick since Rebif may lower your white blood cells necessary to fight infections. Stay away from others with the flu, or other contagious conditions. Inform your doctor immediately for advice and care if you should develop an infection. Avoid using alcohol while taking Refib since it will increase the risk of liver problems.

Expert Insight

According to Emed.tv, "biologic drugs which are made using live cells or organisms are under different laws than most other medication. The law states that these medicines cannot be made as a generic." Refib is a biological drug. Unless the law changes in the future Rebif will never be available as a generic.

Norma Chew

About this Author

Norma Chew is a retired registered nurse who has been a freelance writer since 1978. Chew's articles have appeared in the Journal of the Association of Operating Room Nurses (AORN), "Point of View Magazine" and "Today's OR Nurse." Chew has a master's degree in health care administration from Nova Southeastern University.

Last updated on: 01/04/10

Article reviewed by Contributing Writer

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