Niacin is a form of vitamin B3 that is sometimes used to treat high cholesterol, circulation problems, migraines, pellagra and a variety of other conditions, according to Medline Plus. Low-dose niacin usually causes only minor side effects, but more than 3g per day can cause serious side effects.
Flushing
The most common side effect of niacin is flushing, which can cause burning, tingling, itching and redness, according to Medline Plus. The flushing is most likely to affect the face, arms and chest and may be accompanied by headache. This problem can be minimized by starting with a low dose of niacin and gradually building up to higher doses. Taking 325mg of aspirin before each niacin dose can also reduce the flushing, according to Medline Plus. The flushing typically calms down as the body adjusts to taking niacin. Alcohol can aggravate the problem.
Serious Side Effects
At high noses, niacin can cause liver damage, gout, ulcers, gallbladder disease, kidney disease and blindness, according to Medline Plus. High doses of niacin can increase the risk of irregular heartbeat, a dangerous condition, according to Medline Plus. It can also cause blood pressure to drop and should be avoided by those with low blood pressure. It can also increase blood sugar, which can be dangerous to people with diabetes.
Other Effects
Niacin can also cause digestive troubles like an upset stomach and gas, according to Medline Plus. Other effects include dizziness and pain in the mouth. It can also worsen allergies because it causes the release of histamine, the chemical responsible for allergic reactions.
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