Effects of Chlorpheniramine Maleate

Chlorpheniramine maleate is a drug used to treat allergies. It is available in tablet, capsule and syrup forms, and is marketed under the brand names Aller-Chlor and Chlor-Trimeton. Like most drugs, chlorpheniramine may cause side effects that range in severity from mildly bothersome to life-threatening. Discuss side effects with a physician to determine if you should take another drug instead of chlorpheniramine.

Nervous System

Chlorpheniramine can affect the nervous system of anyone using the drug. Possible central nervous system side effects include restlessness, tremor, headache, vertigo, dizziness, convulsions, loss of coordination, confusion, excitability, euphoria, faintness, hysteria, fatigue, nervousness, insomnia, irritability and inflammation of the nerves. Inflammation of the nerves can cause pain, numbness, weakness and even paralysis, and you should report these symptoms to your doctor.

Cardiovascular System

Because chlorpheniramine is an antihistamine, it has the potential to affect the cardiovascular system, which is made up of the heart and blood vessels. This drug can cause slow heart rate, heart palpitations, fast heart rate, increased heart rate due to stimulation of the nerves in the heart, and a drop in blood pressure upon standing. If these side effects occur, seek medical attention to prevent the serious consequences of changes in cardiac function.

Gastrointestinal System

Most drugs taken orally have the potential to cause digestive system side effects. Chlorpheniramine has been linked to diarrhea, nausea, indigestion, constipation and vomiting. These side effects can be reduced or prevented by taking chlorpheniramine with food, which can protect the stomach from irritation caused by medications. Chlorpheniramine has also be associated with increased appetite and weight gain.

Respiratory System

Antihistamines like chlorpheniramine maleate can depress respiratory function and change a person's breathing. Chlorpheniramine has been associated with wheezing, thickening of the secretions from the lungs, chest tightness and respiratory depression. If these side effects occur, consult a physician immediately to determine if you should stop taking this drug.

Eye, Ears, Nose and Throat

Chlorpheniramine can affect the eyes, ears, nose and throat (EENT) of users. The drug may cause dry throat, nasal congestion (stuffy nose), ringing in the ears, sore throat, dry throat, blurred vision, double vision and swelling of the inner ear. Consult with a physician before trying to treat any of these side effects with over-the-counter drugs. These drugs can interact with chlorpheniramine and cause more serious side effects.

Genitourinary System

Users of chlorpheniramine may experience changes in the urinary and reproductive systems. According to Cerner Multum, women who take chlorpheniramine may experience an early menstrual period. This drug has also been linked to painful urination, urinary frequency, difficulty urinating and retention of urine. Report these urinary side effects to a physician for evaluation. It may be necessary to reduce the dose of chlorpheniramine or use a different drug to avoid these side effects.

General Effects

Chlorpheniramine maleate side effects can also include chills, sensitivity to light, excessive sweating and allergic reactions to the drug. Laboratory test results can also change as a result of taking chlorpheniramine. The drug has been associated with low platelet count, lack of red blood cells and a lack of white blood cells.

References

Article reviewed by Elizabeth Ahders Last updated on: Oct 20, 2009

Must see: Photo Galleries

Member Comments