Alli, known by the generic name orlistat, is the non-prescription version of Xenical, a medication prescribed for weight loss. Alli causes weight loss by blocking the absorption of some of the fat that is eaten in the diet. It must be taken in combination with a low-calorie diet that contains no more than 30 percent of its calories from fat, according to Drugs.com. Alli is only approved for adults age 18 and over.
Loss of Bowel Control
Because Alli blocks the absorption of fat in the intestines, it can cause gas with an oily discharge, oily spots on the undergarments and an urgent or uncontrollable need to have a bowel movement. These effects are common and are considered "treatment effects," or positive signs that the drug is blocking fat from being absorbed, Drugs.com states.These effects will increase if more fat than recommended -- 15 g per meal -- is eaten.
Risk of Liver Damage
The FDA issued a safety alert warning of the risk of serious liver damage resulting from use of Alli. Although rare, cases have been reported. Dieters should stop taking Alli immediately and contact a physician if signs of liver injury, such as yellowing of the skin or eyes, loss of appetite, nausea, itching, dark urine or light-colored stools are experienced, the FDA warns.
Difficulty Absorbing Fat-Soluble Vitamins
Vitamins A, D, E and K are fat-soluble vitamins that are absorbed along with dietary fat. Since Alli decreases the absorption of fat, it can also decrease the absorption of these necessary nutrients. Dieters should take a multivitamin and mineral supplement two or more hours before or after taking Alli to prevent deficiencies, according to Drugs.com.
Requires Discipline and Willpower
Successful weight loss with Alli requires users to cut calories, count fat grams and exercise, just as they would when dieting without using Alli. When Alli is used as directed, dieters may lose 50 percent more weight than they would have through diet and exercise alone. Simply taking Alli without following a diet and exercise program will not result in successful weight loss, according to the American Council on Exercise.
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