Rhabdomyolysis is a condition that is characterized by the breakdown of muscle fibers. When muscle fibers break down, the contents are released into the bloodstream. These contents are called myoglobin. The kidney filters myoglobin from the bloodstream, and the myoglobin can break down into harmful compounds. Rhabdomyolysis can be caused by trauma or any condition that causes damage to skeletal muscle, including heat stroke, seizures and the use or overuse of certain drugs such as cocaine and statins. Rhabdomyolysis has long-term effects that are serious and life-threatening.
Acute Tubular Necrosis
Acute tubular necrosis is a disorder of the kidneys. It is characterized by damage to the tubule cells in the kidneys. The effects of acute tubular necrosis are severe. They include a decrease in the level of consciousness, nausea and vomiting. Coma can result from this disorder. There can be a state of delirium or confusion. Fluid retention associated with acute tubular necrosis can lead to a general swelling. The disorder is also associated with a state of lethargy and drowsiness.
Acute Kidney Failure
Acute kidney failure is a condition characterized by the kidney's inability to remove waste products from the bloodstream and to concentrate urine without losing electrolytes. Symptoms of acute kidney failure include bloody stools, high blood pressure, fatigue, nose-bleeds, nausea, vomiting and changes in urination patterns, including the cessation of urination. This condition can be life threatening.
Shock
As muscle fibers break down, fluid can move into the muscle from the bloodstream, reducing the volume of blood in the body. This can lead to shock. Symptoms of shock can include joint pain, fatigue and seizures.
Myalgia
Myalgia is a condition characterized by muscle pain. The pain can be spread out over different muscles and include other associated tissues such as tendons and ligaments. There can also be a weakness of muscles that results from the muscle fiber breaking down over time.
