It's unlikely you'll ever drink an entire five-liter box of wine in a day. However, you may want to know how many calories it contains overall --- or how many you'll be consuming over time.
A serving of red wine has more calories than a serving of white wine. A 5 oz. glass of red is 125 calories, compared to 121 calories in a 5 oz glass of white, according to the U.S. Department of Agriculture. Per ounce, red wine has 25 calories and white has 24.
It takes roughly 34 fluid ounces to make up a liter. That means a liter of red wine has about 850 calories. It also means a liter of white wine has about 816 calories.
Multiplying those 850 calories in your red wine liter by five results in 4,250 total calories for a 5-liter box of red wine. Doing the same with the 816 calories in your liter of white wine, multiplied by five, produces 4,080 calories per box.
White wines have a slightly less alcohol in them than red wines. Whites average 12 percent alcohol, whereas reds average around 14 percent.