Diet and exercise are your best options for fighting unwanted pounds. If these methods, however, aren't working, weight loss drugs might be an option. The Food and Drug Administration approved orlistat for long-term weight loss. Before taking this medication, it's important to understand how it works and the potential side effects.
How It Works
Orlistat, an oral medication taken by mouth up to three times daily, works by limiting the intestines' ability to absorb fat. Orlistat is taken during a meal or as much as 1 hour after meal time. This medication is available in nonprescription form, called Alli. Alli is a weaker version of orlistat.
Benefits
Using orlistat in conjunction with regular exercise and a low-calorie diet may result in five to 10 percent weight loss within one year, according to the Mayo Clinic website. Losing weight can minimize your risk for high blood pressure, insulin issues, high blood glucose levels and high lipid levels.
Considerations
Orlistat isn't a drug for dropping a few pounds. This medication is designed for people struggling with a body mass index of 30 or higher, or obesity. If you struggle with obesity related health concerns, such as high blood pressure or diabetes, and have a body mass index of 27 or higher, you may also qualify.
Your doctor will consider your entire health history, current medications and potential drug interactions to determine if taking orlistat is the right choice for your health.
Misconceptions
Some people think orlistat weight loss is long-term. However, when you stop taking the medication, you are at risk for regaining the lost weight, according to the MayoClinic website.
Orlistat must also be used with a healthy diet and regular physical activity. The MayoClinic website recommends getting a minimum of 2 hours and 30 minutes of exercise each week. You also need two strength-training sessions weekly.
Warnings
The Food and Drug Administration is reviewing the safety of orlistat because of liver injury reports, according to MayoClinic. Risks associated with taking orlistat and liver injury haven't been established yet, but it's important to watch for potential symptoms of liver injury. Symptoms may include brown urine, weakness, unexplained fever and jaundice.
Discuss the potential risks versus benefits with your doctor before taking this medication. Also, contact your medical insurance plan about coverage. Some insurance companies don't cover orlistat.
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