Glucosamine, an amino sugar, is one of the major components in the cartilage of the joint. Treating arthritis with glucosamine supplements might slow the deterioration of the cartilage, relieving pain while improving joint mobility.
With Chondroitin
Chondroitin is a component of the protein that gives cartilage elasticity. Some arthritis sufferers claim the combination of glucosamine and chondroitin gives pain relief.
Expert Insight
To test those claims, the National Institutes of Health (NIH) conducted a study of 1,583 people with arthritis (see Reference 3). They specifically tested the benefits of glucosamine alone, and glucosamine with chondroitin, in comparison to celecoxib, an anti-inflammatory drug sold as Celebrex.
Study Conclusion
The NIH study suggested that the use of glucosamine with chondroitin is safe and beneficial to those with moderate to severe pain. Because the number of study participants was small, however, further testing will be conducted to substantiate these results. The supplement did not appear to be a helpful treatment for those experiencing mild pain.
Dosage
The recommended dose of glucosamine is 1,500 mg (with or without chondroitin) per day. It may be taken in tablet, capsule, power or liquid form.
Timeline
Glucosamine should be taken daily for a month before evaluating its effects. Though it works similarly to NSAIDs (non-steroidal anti-inflammatories) in relieving arthritis pain, it takes longer to work.
Warning
Glucosamine supplements are most often made from the shells of shellfish (like crab, shrimp or lobster). They could be dangerous if taken by anyone with a shellfish allergy.
Before taking any of these supplements, consult your physician.
